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Science a B Interleukins // Interleukins

Interleukins Interleukins are a group of small signaling proteins, also known as cytokines, that are produced by various cells in the immune system. They play a vital role in regulating immune response by performing a range of functions, such as helping to locate foreign pathogens, driving the maturation and activation of immune cells and mediating cellular communication.

There are over 30 different types of interleukins, each with its own unique set of functions. Interleukins attach to specific receptors on the surfaces of immune cells, pathogens, and even tumor cells, triggering a series of events that can activate or suppress the immune system to stop damage.

It's increasingly clear that interleukins have value beyond the human immune system. Many tumors secrete factors that dampen T cell and other immune cell responses in their microenvironment, enabling these tumors to thrive. However, interleukins have the potential to activate protective immune cells, thus enabling the immune system to reverse the inhibitory effect of the tumor microenvironment and eliminate cancer. Not only that, but many of these immune cells rely on the presence of interleukins for their activity, making these interleukins essential components of immune responses. As research continues on these molecules, their potential applications in the treatment of cancer and other diseases are being explored.

Product pipeline

Product Technology Indication Status
ARS02
SC Low Dose ||-2
Monotherapy for multiple neurodegenerative conditions
IND
ARS02C
SC Low Dose ||-2 Combination
Combination of Treg-Based therapy across multiple therapeutic areas
Non clinical
ARS15
IL-15
Solid Tumors
FIH
ARS10
IL-15 – Fusion protein
Cancer
Pre clinical

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ARScience Bio’s team has over 20 years of experience in cytokine and immunomodulator development and manufacturing. We have built strong partnerships with leading academic institutions and clinical groups to develop novel indications for our portfolio of products.

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